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Progress in research on promoting wound healing by self pumping viscous exudate from physical and chemical institutions

Time:2024-04-15 06:28:12
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High viscosity exudate hinders wound healing, easily leading to wound deterioration, infection, and sustained inflammatory stimulation, which is a challenge faced by clinical wound treatment. The ideal wound dressing should remove excess exudate as needed and in a timely manner. However, the inherent characteristics of high viscosity and weak fluidity of viscous biological fluids hinder effective transport. In clinical practice, it is necessary to frequently use external physical methods to remove viscous biological fluids, but secondary trauma and persistent pain stimulation may occur. Therefore, there is an urgent need to develop a new generation of medical dressings with the ability to efficiently export viscous biological fluids.

Recently, Wang Shutao, a researcher at the Institute of Physical and Chemical Technology of the Chinese Academy of Sciences, and Shi Lianxin, an associate researcher, reported on the self pumping oil gel dressing with hydration hydrogel channels. This dressing can achieve rapid healing of diabetes wounds by removing excessive viscous biological fluid from the wound in one direction. Compared with commercial hydrocolloid dressings, this dressing has an increased dermis remodeling rate of about 14.3% and a shortened wound healing time of about 33.3%. This achievement provides new ideas for the treatment of chronic wounds related to viscous biological fluids.

The relevant research results are titled A Viscous biofluid Self pumping Organohydrogel Dressing to Accelerate Diabetic Wound Healing and published in Advanced Materials. The research work was supported by the National Natural Science Foundation of China and the Youth Innovation Promotion Association of the Chinese Academy of Sciences.

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